Barbie Blank was a full-time bikini model for Venus Swimwear until she signed a developmental contract with the WWE (World Wrestling Entertainment) on May 13, 2006. John Laurinaitis saw her in a bikini catalog and contacted her modeling agency about hiring her and Victoria Crawford. Barbie signed with WWE after her agent advised her to, and reported to OVW (Ohio Valley Wrestling) for further training. Even though Barbie was called onto the main roster, she flies back to Louisville, Kentucky to OVW once a week and works at house shows as a ring announcer and referee along with Crawford, going by her ring name Alicia Fox. On June 24, 2006 at OVW TV tapings, Barbie made her OVW debut as Kelly and participated in a bikini contest. Barbie, now known as "Kelly Kelly" had no prior wrestling experience before being signed by the WWE. She was the youngest female member on the WWE/ECW roster starting out at the age of 19. Barbie made her debut known as "Kelly Kelly" on the June 13, 2006 edition of ECW. In July 2008, she was drafted to the WWE Raw brand. Then in April 2010, she was drafted to the Smackdown brand. After the brand switches between both shows she was drafted back to Raw in April 2011. She won her first WWE Divas Championship in June against Brie Bella and then lost the title in October to Beth Phoenix. Following many unsuccessful attempts to win the WWE Divas Championship, she later participated in several tag team matches. At WrestleMania XXVIII (2012), she teamed with Extra (1994) correspondent Maria Menounos to defeat Beth Phoenix and Eve Torres in a tag team match. In June, she took time off from WWE before returning in August defeating Eve Torres in a singles match. In September 2012, she was released from WWE. She later stated in an interview that she needed time off to heal from a neck injury and had plans to model.
Kelly returned to WWE by being featured in a backstage interview for WWE's official website during the February 13, 2017, episode of Raw. She later appeared during WrestleMania weekend, including at the Hall of Fame induction ceremony, and appeared on an episode of the WWE Network exclusive Table for 3. On January 22, 2018, Kelly appeared at the Raw 25 Years special, being honored as one of the historic women of WWE. A few days later, on January 28 at the Royal Rumble event, Kelly competed in the first women's royal rumble match, where she entered at number 19, and was eliminated by Nia Jax.
Blank is one of the cast members of the E! reality television series WAGS, which began airing in August 2015 and features a look into the personal lives of the wives and girlfriends of sportsmen.
Blank made her acting debut on the January 30, 2017, episode of Days of Our Lives, appearing in a scene as a waitress who gives information to one of the show's main characters.