Melody Anderson was as a guest star in the 1977 series 'Logan's Run' and as a "Sweathog" in a 1977 episode of 'Welcome Back Kotter'. She made numerous appearances on television, including 'Archie Bunker's Place', 'Battlestar Galactica', 'Dallas', 'T.J. Hooker', 'CHiPs', the pilot episode of 'The A-Team' and 'The Fall Guy'. She had recurring roles on 'St. Elsewhere' and 'Jake and the Fatman'. She was the female lead of the NBC 1983 series 'Manimal'. She was a guest star in the 'Murder, She Wrote' episode "Prediction: Murder" in 1989.
Anderson played the female lead "Dale Arden" in 'Flash Gordon' (1980) and Janet Gillis in 'Dead and Buried (1981). In 1983, she played the title role in a made-for-television film called 'Policewoman Centerfold', in whuch her character, a divorced police officer, is fired after posing nude for a men's magazine (based loosely on the true story of Springfield Ohio patrolwoman Barbara Schantz, who was subsequently fired from her job after posing nude in Playboy magazine in the early 1980's.
In 1986, she appeared with Nicolas Cage in 'The Boy in Blue' and with Chuck Norris in 'Firewalker'. She starred in the made-for television movie 'Beverly Hills Madam' (1986), which starred Faye Dunaway. From 1992-93, Anderson portrayed Natalie Marlowe, and briefly her twin sister Janet Dillon, on the soap opera 'All My Children'. She starred as Edie Adams in the television film 'Ernie Kovacs: Between the Laughter', opposite Jeff Goldblum as Ernie Kovacs and played the coveted role of Marilyn Monroe in the television movie 'Marilyn & Bobby: Her final Affair (1993), Her last television appearance was in 1995 as a guest star in the short-lived CBS revival of 'Burke's Law'.